Linked Color Imaging Demonstrates Characteristic Findings in Semi-Pedunculated Gastric Adenocarcinoma in Helicobacter Pylori-Negative Normal Mucosa

Yuji Hiraoka1, Yoshimasa Miura1, Hiroyuki Osawa1, Mio Sakaguchi2, Masato Tsunoda1, Alan Kawarai Lefor3, Hironori Yamamoto1

Clin Endosc. 2020 Aug 21. doi: 10.5946/ce.2020.059. Online ahead of print.

Linked color imaging (LCI) provides bright observation suitable for screening of the entire stomach [1], and its high color contrast to the surrounding mucosa makes it easier to detect early malignant lesions [2,3]. Compared to white light imaging, LCI enhances subtle differences in the color tone by advanced post processing steps [4]. LCI has a higher emission intensity of 410 nm, which can influence the mucosal color of various lesions [1,4]. Clear images of gastric cancer have been reported in the background with a history of Helicobacter pylori infection. Here, we report a semi-pedunculated gastric adenocarcinoma in H. pylori-negative normal mucosa imaged using LCI.

1 Division of Gastroenterology, Department of Medicine, Jichi Medical University,Tochigi, Japan
2 Department of Pathology, Jichi Medical University,Tochigi, Japan
3 Department of Surgery, Jichi Medical University,Tochigi, Japan