Naohisa Yoshida 1, Osamu Dohi 1, Ken Inoue 1, Satoshi Sugino 1, Ritsu Yasuda 1, Ryohei Hirose 1, Yuji Naito 1, Yutaka Inada 2, Takaaki Murakami 3, Kiyoshi Ogiso 4, Yukiko Morinaga 5, Mitsuo Kishimoto 5, Yoshito Itoh 1
International Journal of Colorectal Disease 2020 Feb 22[Online ahead of print]
Objectives: An endoscope with a light-emitting diode (LED) light source which has a 2-mm close-distance observation function without magnification, has been marketed, enabling linked color imaging (LCI) and blue laser imaging (BLI) for tumor detection and characterization. We analyzed the efficacy of a LED endoscope compared to a LASER endoscope.
Methods: We retrospectively reviewed 272 lesions observed using the LED endoscopic system (Fujifilm Co., Tokyo, Japan) from May 2018 to September 2019. The Japanese NBI Classification was used for tumor characterization. We analyzed the diagnostic accuracy and confidence level. Sixty-one lesions observed with both the LED and magnified LASER endoscopes were also analyzed to compare the diagnostic accuracy. Regarding the tumor detectability, we calculated color difference values (CDVs) and brightness values (BVs) of white-light imaging, BLI, and LCI modes between the two endoscopes for each tumor.
Results: The mean polyp size was 9.2 ± 11.3 mm. Histology showed 71 sessile serrated lesions, 193 adenoma and high-grade dysplasias, and 8 T1 cancers. The diagnostic accuracy of tumors ≥ 10 and < 10 mm was 72.0% and 92.9% (p < 0.001), respectively and the high confidence rate was 93.8%. The diagnostic accuracy of LED (77.0%) was a little higher than that of LASER without magnification (65.6%, p = 0.16) but was not inferior to that of LASER with magnification (82.0%, p = 0.50). The respective CDVs of LED and LASER endoscopes were 20.6 ± 11.2 and 21.6 ± 11.2 for LCI (p = 0.30), and the respective BVs were 210.0 ± 24.2 and 175.9 ± 21.1 (p < 0.001).
Conclusions: A LED endoscope with close-distance observation improved tumor detection and characterization due to high brightness.
1 Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
2 Department of Gastroenterology, Fukuchiyama City Hospital, Kyoto, Japan
3 Department of Gastroenterology, JCHO Kyoto Kuramaguchi Medical Center, Kyoto, Japan
4 Department of Gastroenterology, Osaka General Hospital of West Japan Railway Company, Osaka, Japan
5 Department of Surgical Pathology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan